University of Florida Health Proton Therapy Institute for Cancer Treatment

With medical technology constantly evolving, Gilbane is providing innovative construction management solutions that allow cancer centers and proton therapy facilities to expand and deliver state-of-the-art treatment to their patients.

expanding and enhancing a Proton therapy facility

As one of the first proton therapy centers in America, constructed over 10 years ago, the University of Florida (UF) Health Proton Therapy Institute  is at the forefront of radiation oncology. Cancer treatment, and in particular particle therapy technology, is constantly evolving. UF Health Proton Therapy Institute set out to develop a strategy to upgrade their existing three gantries with the latest technology; however, impacting their current patient treatment capacity was simply not an option. This challenge was the stimulus to consider expanding utilizing a compact “single room” treatment system.

The expansion will be approximately 10,000 SF over two floors constructed immediately adjacent to the east side of the current building and will ultimately increase treatment capacity by 33%. The new expansion will house Ion Beam Applications’ Proteus©One compact proton therapy equipment for state-of-the-art treatment. In addition to the complex challenges that come along with proton therapy construction, this project requires tremendous efforts to manage a site bordered by the existing facility, Hogan Creek and two busy city streets. Once complete, the new patient treatment capacity will allow UF Health Proton Therapy Institute to phase in upgrades to the original three gantries while always maintaining their current treatment capacity.

The project engineer is Affiliated Engineers, Inc.

10 Minutes with … Gilbane CEO Mike McKelvy

Leading the Way with Lean

SLAC National Laboratory Equipment Removal Sectors 0 to 10, Menlo Park, CA

Detailed coordination efforts allowed the equipment removal to be complete one month ahead of schedule, allowing SLAC to have co-occupancy with other contractors for construction of the new LCLS II accelerator.

GILBANE COMPLETES HIGH PROFILE EQUIPMENT REMOVAL PROJECT AT SLAC

Gilbane successfully completed 100% removal of equipment from the 1 km long LINAC accelerator at SLAC National Laboratory under a highly aggressive schedule with a required completion date of December 31, 2016.  Through specialized sequencing of construction crews, all equipment was removed from the first floor (Klystron Gallery) and the underground accelerator housing before November 30, 2016, allowing a required co-occupancy for construction of the LCLS II.

The transport of removed components out of the Accelerator Housing required a great deal of planning and coordination. Due to the lack of ventilation, only electric forklifts were feasible for use inside the housing. In addition, the maneuverability was restricted by the width of the tunnel. In order to remove the 40 foot long accelerator structures, custom girders (dollies) were fabricated, which allowed workers to roll the accelerator structures out of the tunnel without the use of heavy equipment. This safer approach increased the efficiency of the work flow and enhanced overall safety for the project.

Because of radiological hazards identified in the Accelerator Housing, field crews performed a portion of the scope under radiological controls and oversight. To ensure that all radiological wastes were identified prior to removal from the work area, Gilbane’s subcontractor performed radiological surveys for every component removed from the radiologically controlled areas within the Accelerator Housing.

Genentech, Inc. Biopharmaceutical Manufacturing Campus

Gilbane’s proactive safety program resulted in nearly two million safe work hours without a lost time incident on this important project.

Value engineering workshops generated millions in savings to the client

The project included a biopharmaceutical manufacturing building, a laboratory/ office facility, warehouse, and support buildings on a 100-acre greenfield site. Gilbane devised a fast-track, phased construction approach closely tied to Genentech’s manufacturing timetable for products currently in development. Portions of the project were turned over to the owner as they were completed, allowing Genentech to get the necessary start-up and validation processes underway to bring the facilities on-line and start production sooner.

Using a partnering approach, Gilbane worked with the owner and engineer to develop a mission statement, identifying common goals and the factors critical to success. Gilbane added value to the partnership with its extensive technical knowledge of pharmaceutical and biotech facilities. Two Gilbane-led value engineering workshops identified 147 proposals which were accepted by the owner, generating savings of over $35 million.

Gilbane developed a project specific safety program for the Genentech project site, which was closely integrated with the Contractor Controlled Insurance Program (CCIP). The proactive safety program began with first day orientation for every worker and resulted in nearly two million safe work hours without a lost time incident. The success of the Gilbane Safety Program resulted in a $3.5 million savings in insurance costs. Gilbane was also recognized by the AGC of California with its Safety Excellence Award two years in a row. The Gilbane Quality In Construction (QIC) process was implemented on the Genentech project from day one. Over the course of construction 1,370 QIC inspections and events took place. At substantial completion of the high-quality biotech manufacturing building, there were only 114 items on the punch list – less than one item for each of the 205 rooms. As a result of the QIC process, a world-class biotech facility was built with a minimal punch list, resulting in the smoothest start-up of any new facility in Genentech’s 25-year history.

Biopharmaceutical Manufacturing Facility

Early partnering through design-assist offers the opportunity to provide input into the project schedule, logistics planning, long-lead procurements, and construction phasing.

New state-of-the-art biopharmaceutical manufacturing facility

Gilbane is providing comprehensive construction management services for Alnylam Pharmaceuticals’ new 200,000 square foot state-of-the-art manufacturing facility that will supply drug substance for RNAi (RNA interference) therapeutics for Alnylam’s clinical and commercial needs. The facility is expected to be operational in 2018 and will initially employ approximately 150 new full-time employees.

Ryan Hutchins, Senior Vice President, Gilbane spoke of the groundbreaking, “The energy and excitement at the event was contagious and it is sure to grow as the new facility develops from a vision into reality. Construction involving biopharmaceutical facilities requires precision, vital documentation, compliance with stringent regulations and a superior commitment to safety.  The team we have dedicated to this project have exceptional depth of experience constructing biopharmaceutical facilities.  We are truly honored to be a part of Alnylam’s growth in Massachusetts.”

Pima County Psychiatric Hospital & Crisis Recovery Center

Integrated facility design helps ensure security and highest standards of patient care.

Award winning New innovative mental health center

Gilbane provided Program Management services for two new psychiatric facilities for Pima County: the Behavior Health Pavilion and the Crisis Response Center. Composed of two inter-related but functionally distinct structures, the buildings are located adjacent to Banner University Medical Center to take advantage of medical and support services.

Internally, each building is organized into layered zones of patient and support spaces. The Behavioral Health Pavilion houses 96 inpatient acute-care beds, psychiatric urgent and emergent care, psychiatric court hearing rooms, and space for basic clinical studies for neurology and psychiatry.

The Crisis Response Center houses comprehensive screening, assessment, crisis stabilization treatment and triage. Organized around a shared sally port, the integrated facilities provide a secure circulation zone for staff, law enforcement, courtroom personnel, and patient transfers. The project involved related site work including parking lots, and road, drainage, and utility improvements.

Gilbane also provided select transition, planning and management (TPM) services for this project.

Gilbane Breaks Ground on Biopharmaceutical Manufacturing Facility in Norton, Massachusetts

The new 200,000 square foot, state-of-the art Facility Will Support Alnylam Pharmaceuticals Expanding Development Pipeline

AlnylamBoston, MA – April 29, 2016 – State and Community officials, including Charlie Baker, the Governor of Massachusetts; Kimberly Haugstad, Executive Director of the Hemophilia Federation of America; Travis McCready, President and Chief Executive Officer of the Massachusetts Life Sciences Center and Lisa Nelson, Senior District Representative to U.S. Congressman Joseph Kennedy III, were in attendance to celebrate the official breaking of ground for Alnylam Pharmaceuticals, Inc. biopharmaceutical manufacturing facility in Norton, Massachusetts.

Gilbane will serve as construction manager for the new 200,000 square foot state-of-the-art manufacturing facility that will supply drug substance for RNAi (RNA interference) therapeutics for Alnylam’s clinical and commercial needs. The facility is expected to be operational in 2018 and will initially employ approximately 150 new full-time employees. The location of the new facility, selected in close collaboration with Commonwealth and local officials, demonstrates Alnylam’s ongoing commitment to Massachusetts.

“The energy and excitement at the event was contagious and it is sure to grow as the new facility develops from a vision into reality,” said Ryan Hutchins, Senior Vice President.   “Construction involving biopharmaceutical facilities requires precision, vital documentation, compliance with stringent regulations and a superior commitment to safety.  The team we have dedicated to this project have exceptional depth of experience constructing biopharmaceutical facilities.  We are truly honored to be a part of Alnylam’s growth in Massachusetts.”

“We are excited to begin development of our new flagship multi-product manufacturing facility with the Gilbane team,” said Al Boyle, Senior Vice President, Technical Operations at Alnylam. “This facility represents a key next step in Alnylam’s transition toward a commercial stage company.”

About Gilbane Building Company

Gilbane provides a full slate of construction and facilities-related services – from pre-construction planning and integrated consulting capabilities to comprehensive construction management, close-out and facility management services – for clients across various markets. Founded in 1873 and still a privately held, family-owned company, Gilbane has more than 50 office locations around the world. For more information, visit www.gilbaneco.com.

Gilbane has been a leading Boston construction firm since 1946, serving commercial, institutional, and public clients in the Commonwealth including the Genzyme, Fraunhofer Center for Sustainable Energy Systems, University of Massachusetts, Worcester Polytechnic Institute, Tufts University, Verizon, Fidelity Investments, and Bank of America. The Boston office was recently named a Top Charitable Contributor in 2015 by Boston Business Journal. For more information, visit www.gilbaneco.com.

Alnylam
Rendering courtesy of Alnylam

Alnylam to Break Ground on New Manufacturing Facility in Norton, Massachusetts

University of Texas Southwestern Medical Center at Dallas Biotechnology Development Complex Phase 1

The University required a high degree of flexibility in the design of this field of dreams project to accommodate a variety of Biotechnology enterprises

The flexibility of the building provides for the rapid fit up or renovation of spaces to accommodate new users

Gilbane served as construction manager for the University of Texas Southwestern Medical Center at Dallas’s (UTSWMC) new biotechnology building project.

UTSWMC’s “BioCenter at Southwestern Medical District” supports the technology transfer efforts of the “Office of Technology Development.” The University required a high degree of flexibility in the design of this field of dreams project to accommodate a variety of Biotechnology enterprises.

The facility provides lease space for start-up ventures to serve the spectrum of the biotechnology and biomedical device industry. The sixteen foot floor-to-floor height and integrally designed mechanical penthouse allows for the distribution of utilities above ceilings to maximize usable square footage. This design allows any available square foot to be used for either laboratory or office space.

The building’s exterior materials are in keeping with the contextual vocabulary of the existing UTSWMC campus. Sustainably designed, while not submitted for certification, the project could potentially obtain LEED® Silver status. Ample fenestration using highly efficient insulated glazing accommodates daylighting of the interior and visual connectivity of the occupants to the environment. Collaborative spaces, the large break area and vertical circulation lobby for instance, are located along the transept circulation corridor to enhance purposeful and chance meetings of researchers. The interior finishes, selected for aesthetics and durability, work with the spatial experience to promote an inspirational environment; witness this in the relation of three story reception lobby to the transept circulation corridor.

The flexibility of the building both in programmatic function and mechanical systems provides for the rapid fit up or renovation of spaces to accommodate new users. The laboratory module is conservatively established to provide anywhere from 363 square foot labs with ample bench space to as much as 35,000 square feet of contiguous laboratory space. From the structural grid to the exterior glazing the dimensional control is a reflection of the laboratory module. The wide main corridor and abundantly sized dual purpose service/occupant only elevator allows for secure equipment move-in without impairment to personnel circulation. The routing of utilities overhead rather than in a service corridor maximizes the usable square footage; which in turn reduces lease rates. The functional flexibility of the building can support both the wet and dry sciences and any given non-support square foot can be any configuration of laboratory or office and the distribution of looped utility, air and exhaust systems can be easily configured or reconfigured to accommodate the high churn rate generally experienced by a facility with this purpose.